Arrestins:Structure and Function in Vision and Beyond

Arrestins: Structure and Function in Vision and Beyond examines the structural basis of the function of arrestin proteins in the brain. Linking basic, translational, and clinical research, this volume begins with history and basic signaling principles, and expands to the use of proteins as potential therapeutic targets. Multiple cellular activities are detailed, including activation, signaling, GPCR endocytosis, and ERK signaling, with chapters examining both visual and non-visual arrestins in the brain. Experts in their respective fields feature as chapter authors providing concise, yet accessible summaries of the recent developments in GPCR and arrestin science. This book is essential reading for anyone wishing to explore the basic science underlying these signaling proteins and their importance in brain health and neuron dysfunction. Links basic, translational, and clinical research on arrestin and GPCR signaling proteins in the nervous system Features chapters on its vital signaling functions in brain health Includes unique sections on their use as potential therapeutic targets Covers both vision and non-vision arrestins Provides an overview for scientists new to the study of GPCRs and arrestins

Pages: 250

Edition: 01

Publisher: Academic Press, Incorporated

Copyright: 2022

Published: 06/22