Humanized Mice

In a humanized mouse transplanted human tissues and cells show the same biological function as they do in the human body. It has become possible to study the pathophysiology and treatment of human diseases in mice with excellent reproducibility, a remarkable breakthrough. Unsurprisingly, the humanized mouse is proving to be one of the most powerful tools in basic and clinical research. This fascinating and authoritative review considers mouse models that display the characteristics of a range of human cell tissue types but focuses on mice with the human immune system. It also considers the future prospects for developing and using humanized mice in a new era for research in human disease.

Pages: 202

Series: Current Topics in Microbiology and Immunology

Volume: 324

Edition: 01

Publisher: Springer

Copyright: 2008

Published: 06/08

Notes: Print on Demand. Please allow additional time for delivery.